Next Generation Sequencing (NGS) Market, By Technology (WES, WGS, Targeted Sequencing and Resequencing Technique), By Application, By Product & Services, By End Use, And Geography (North America, Europe, Asia Pacific, And Rest Of The World) Analysis, Share, Trends, Size, & Forecast From 2014 2025
REPORT HIGHLIGHT
The next generation sequencing market is estimated to represent a global market of USD 5,618 million by 2017 with growth rate of 9.1%.
Next-generation sequencing (NGS) involves an advanced level of genetic sequencing which is a level above the conventional methods such as capillary electrophoresis-based Sanger sequencing. NGS procedure is a multi-step process where a number of smaller laboratory processes combine to form the whole next-generation sequencing process. This includes pre-sequencing steps of sample preparation, target enrichment, library preparation under NGS pre-sequencing, the sequencing procedure under NGS Sequencing and data warehousing and data interpretation under NGS data analysis in the workflow outlook.
NGS technology is used for the wide array of sequencing approaches such as transcriptome, genome, and epigenome of any organism. Sequencing techniques differ primarily based on the development of DNA/RNA samples, i.e. tissue type, organism, experimental conditions, and others. This technology is very effective and flexible for the variety of study in large genomic centers to small-scale laboratories. NGS sequencing method is different from Sanger sequencing at a fundamental level in which instead of one fragment being expanded a time, over millions of fragments are expanded in simultaneous reactions which greatly enhance the sequencing capabilities.
Market Dynamic
The market is primarily driven by the constant growth in demand for genetic sequencing owing to its cost-effectiveness. According to the National Human Genome Research Institute (NHGRI), and the significant decrease in the costs for genome sequencing have been witnessed since the first Human Genome Project was initiated in 2000. This has led an increase in uptake of genetic sequencing by various end users such as biotechnology companies, pharmaceutical industries and other, leading to driving the market growth. Furthermore, next-generation sequencing technologies have expanded applications in oncology, infectious disorders, and idiopathic diseases analysis. Additionally, with the technological development of whole-genome sequencing, novel avenues of applicability such as human leukocyte antigen (HLA) and prenatal testing have also been developed, supporting the market growth to great extent.
Technology Takeaway
In terms of technological level, next-generation sequencing is categories into Whole Exon Sequencing (WES), Whole Genome Sequencing (WGS), Targeted Sequencing and Resequencing Technique. These approaches encompass smaller fragment length sequencing approaches such as de novo sequencing and others. NGS resequencing and de novo sequencing provide laboratories with a capability to produce high throughput sequencing results.
Targeted sequencing captured the significant share of the global market. This sequencing enables researchers to isolate and the sequence-specific subset of genes of the genome. It allows researchers to focus data analysis and specific area of interest time with higher coverage level. For example, targeted resequencing method can cover more than 500–1000× region of genome compared to the traditional WGS study (achieves coverage levels of 30–50× per genome). This advantage help researcher to identify rare variations which are impossible with WGS and CE-based sequencing techniques.
Application Takeaway
Oncology, Reproductive Health, Clinical Investigation, Consumer Genomics, Immune Monitoring, and others are categorized under application segment. NGS technique has had the greatest applications for clinical research and development of cancer diagnostics and therapeutics. NGS has major applications in oncology wherein it is used to sequence and Catalogue gene mutations for further development of novel cancer diagnostic and therapeutic methodologies. With the expected reduction in the cost of whole-genome sequencing, applications of NGS in oncology will witness the significant increase in demand throughout the forecast period.
Product & Services Takeaway
In terms of products & services, the market is divided as Pre-Sequencing Products (i.e. NGS library preparation kits, NGS semi-automated library preparation, NGS automated library preparation, Clonal amplification), Sequencing Services, and Data Analysis. Pre-Sequencing phase includes the sample preparation processes that are undertaken prior to the sequencing step. The end-user segment is bifurcated as Academic Research, Hospital Settings, Clinical Laboratories, and others.
North America Next Generation Sequencing Market
Regional Takeaway
Regionally, North America and Europe accounted for the largest share of the global market. Rising research and development activities coupled with increasing demand for advanced sequencing techniques support the market growth in these regions. Furthermore, rapid penetration of personalized medicine and companion diagnostics techniques further boost the market growth. On another side, the establishment of organizations such as Beijing Genomics Institute (BGI) supports the overall Asia Pacific market growth. For instance, it has been reported that BGI has installed over 120 HiSeq (Illumina) 2000 genome sequencers in 2010. Owing to this, BGI NGS laboratory in Hong Kong is considered to be among the few very high capacity next-generation genome sequencing facilities.
Key Vendor Takeaway
Companies such as Illumina, Inc., Qiagen, Agilent Technologies, Genomatix GmbH, and Roche are profiles in the study. Wide product offering coupled with increasing research and development activities helped companies to achieve significant revenue share. For example, Illumina offers the wide range of NGS instruments, ranging from the benchtop MiniSeq System to the advanced NovaSeq 6000 System. The company presents comprehensive solutions for NGS workflow such as sequencing instrument, library preparation kits, bioinformatics and automated data analysis tools.
The market size and forecast for each segment has been provided for the period 2014 to 2025, considering 2015 as the base year. The report also provides the compounded annual growth rate (% CAGR) for the forecast period 2016 to 2025 for every reported segment.
The years considered for the study are:
- Historical Year – 2014 & 2015
- Base Year – 2015
- Estimated Year – 2016
- Projected Year – 2025
TARGET AUDIENCE
- Traders, Distributors, And Suppliers
- Manufacturers
- Hospitals
- Government and Regional Agencies and Research Organizations
- Consultants
- Distributors
SCOPE OF THE REPORT
The scope of this report covers the market by its major segments, which include as follows:
MARKET, BY TECNOLOGY
- Whole Exon Sequencing (WES)
- Whole Genome Sequencing (WGS)
- Targeted Sequencing
- Resequencing Technique
MARKET, BY APPLICATION
- Oncology
- Reproductive Health
- Clinical Investigation
- Consumer Genomics
- Immune Monitoring
- Others
MARKET, BY PRODUCT & SERVICES
- Pre-Sequencing Products
- Sequencing Services
- Data Analysis
MARKET, BY END USE
- Academic Research
- Hospital Settings
- Clinical Laboratories
- Others
MARKET, BY REGION
- North America
- Europe
- Asia Pacific
- Rest of the World
MARKET, BY COUNTRY
- Further Breakdown of The North America Market
- U.S.
- Canada
- Further Breakdown of The Europe Market
- Germany
- France
- Rest of Europe
- Further Breakdown of The APAC Market
- India
- China
- Rest of APAC
- Further Breakdown of The Rest of the World Market
- Middle East and Africa
- Latin America
TABLE OF CONTENT
1. NEXT GENERATION SEQUENCING (NGS) MARKET OVERVIEW
1.1. Study Scope
1.2. Base Year
1.3. Assumption and Methodology
2. EXECUTIVE SUMMARY
2.1. Key Market Facts
2.2. Geographical Scenario
2.3. Companies in the Market
3. NEXT GENERATION SEQUENCING (NGS) KEY MARKET TRENDS
3.1. Market Drivers
3.1.1. Impact Analysis of Market Drivers
3.2. Market Restraints
3.2.1. Impact Analysis of Market Restraints
3.3. Market Opportunities
3.4. Market Future Trends
4. NEXT GENERATION SEQUENCING (NGS) INDUSTRY STUDY
4.1. Company Activity Analysis
4.2. Regulatory Framework Analysis
4.3. Market Attractiveness Analysis
4.4. Value Chain Analysis
5. NEXT GENERATION SEQUENCING (NGS) MARKET LANDSCAPE
5.1. Market Share Analysis
5.2. Key Innovators
6. NEXT GENERATION SEQUENCING (NGS) MARKET – BY TECHNOLOGY
6.1. Overview
6.2. Whole Exon Sequencing (WES)
6.2.1. Overview
6.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
6.3. Whole Genome Sequencing (WGS)
6.3.1. Overview
6.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
6.4. Targeted Sequencing
6.4.1. Overview
6.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
6.5. Resequencing Technique
6.5.1. Overview
6.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
6.6. Others
6.6.1. Overview
6.6.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7. NEXT GENERATION SEQUENCING (NGS) MARKET – BY APPLICATION
7.1. Overview
7.2. Oncology
7.2.1. Overview
7.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.3. Reproductive Health
7.3.1. Overview
7.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.4. Clinical Investigation
7.4.1. Overview
7.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.5. Consumer Genomics
7.5.1. Overview
7.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.6. Immune Monitoring
7.6.1. Overview
7.6.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
7.7. Others
7.7.1. Overview
7.7.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8. NEXT GENERATION SEQUENCING (NGS) MARKET – BY PRODUCT & SERVICES
8.1. Overview
8.2. Pre-Sequencing Products
8.2.1. Overview
8.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.3. Sequencing Services
8.3.1. Overview
8.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
8.4. Data Analysis
8.4.1. Overview
8.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
9. NEXT GENERATION SEQUENCING (NGS) MARKET – BY END USE
9.1. Overview
9.2. Academic Research
9.2.1. Overview
9.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
9.3. Hospital Settings
9.3.1. Overview
9.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
9.4. Clinical Laboratories
9.4.1. Overview
9.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
9.5. Others
9.5.1. Overview
9.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10. NEXT GENERATION SEQUENCING (NGS) MARKET– BY GEOGRAPHY
10.1. Introduction
10.2. North America
10.2.1. Overview
10.2.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.2.3. U.S.
10.2.3.1. Overview
10.2.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.2.4. Canada
10.2.4.1. Overview
10.2.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.3. Europe
10.3.1. Overview
10.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.3.3. France
10.3.3.1. Overview
10.3.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.3.4. Germany
10.3.4.1. Overview
10.3.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.3.5. Rest of Europe
10.3.5.1. Overview
10.3.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.4. Asia Pacific (APAC)
10.4.1. Overview
10.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.4.3. China
10.4.3.1. Overview
10.4.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.4.4. India
10.4.4.1. Overview
10.4.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.4.5. Rest of APAC
10.4.5.1. Overview
10.4.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.5. Rest of the World
10.5.1. Overview
10.5.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.5.3. Latin America
10.5.3.1. Overview
10.5.3.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
10.5.4. Middle East and Africa
10.5.4.1. Overview
10.5.4.2. Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
11. KEY VENDOR ANALYSIS
11.1. Illumina, Inc.
11.1.1. Company Overview
11.1.2. SWOT Analysis
11.1.3. Key Developments
11.2. Qiagen
11.2.1. Company Overview
11.2.2. SWOT Analysis
11.2.3. Key Developments
11.3. Agilent Technologies
11.3.1. Company Overview
11.3.2. SWOT Analysis
11.3.3. Key Developments
11.4. Genomatix GmbH
11.4.1. Company Overview
11.4.2. SWOT Analysis
11.4.3. Key Developments
11.5. Roche
11.5.1. Company Overview
11.5.2. SWOT Analysis
11.5.3. Key Developments
*Client can request additional company profiling as per their specific requirements
12. 360 DEGREE ANALYSTVIEW
13. APPENDIX
13.1. Research Methodology
13.2. Abbreviations
13.3. Disclaimer
13.4. Contact Us
List of Tables
Table 1 List of Acronyms
Table 2 Key Market Facts, 2014 – 2025
Table 3 Market Drivers: Impact Analysis
Table 4 Market Restraint: Impact Analysis
Table 5 Market Opportunity: Impact Analysis
Table 6 PESTLE Analysis
Table 7 Porter’s Five Forces Analysis
Table 8 Company Market Share Analysis
Table 9 Global NGS Market Analysis, Forecast, and Y-O-Y Growth Rate, 2014 – 2025, (US$ Million)
Table 10 NGS Market, by Technology, 2014 – 2025 (USD Million)
Table 11 NGS Market, by Application, 2014 – 2025 (USD Million)
Table 12 NGS Market, by Product & Services, 2014 – 2025 (USD Million)
Table 13 NGS Market, by End Use, 2014 – 2025 (USD Million)
Table 14 NGS Market, by Geography, 2014 – 2025 (USD Million)
Table 15 North America NGS Market, 2014 – 2025 (USD Million)
Table 16 U.S. NGS Market, 2014 – 2025 (USD Million)
Table 17 Canada NGS Market, 2014 – 2025 (USD Million)
Table 18 Europe NGS Market, 2014 – 2025 (USD Million)
Table 19 France NGS Market, 2014 – 2025 (USD Million)
Table 20 Germany NGS Market, 2014 – 2025 (USD Million)
Table 21 Asia Pacific NGS Market, 2014 – 2025 (USD Million)
Table 22 China NGS Market, 2014 – 2025 (USD Million)
Table 23 India NGS Market, 2014 – 2025 (USD Million)
Table 24 Latin America NGS Market, 2014 – 2025 (USD Million)
Table 25 MEA NGS Market, 2014 – 2025 (USD Million)
List of Figures
Figure 1 Research Methodology
Figure 2 Research Process Flow Chart
Figure 3 Comparative Analysis, by Geography, 2016-2025 (Value %)
Figure 4 Regulatory Framework Analysis
Figure 5 Value Chain Analysis Analysis
Figure 6 NGS Market, by Technology, 2014 – 2025 (USD Million)
Figure 7 NGS Market, by Application, 2014 – 2025 (USD Million)
Figure 8 NGS Market, by Product & Services, 2014 – 2025 (USD Million)
Figure 9 NGS Market, by End Use, 2014 – 2025 (USD Million)
Figure 10 NGS Market, by Geography, 2014 – 2025 (USD Million)
